2. Cell Cycle/DNA Damage Epigenetics
  3. HDAC
  4. HDAC6-IN-9

HDAC6-IN-9 (compound 12c) is a potent and selective HDAC6 inhibitor with IC50 values of 11.8, 15.2, 4.2, 139.6, 21.3 nM for HDAC1,HDAC3, HDAC6, HDAC8, HDAC10, respectively. HDAC6-IN-9 shows anti-proliferative activities.

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HDAC6-IN-9 Chemical Structure

HDAC6-IN-9 Chemical Structure

CAS No. : 2796282-58-9

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HDAC6-IN-9 Related Antibodies

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Description

HDAC6-IN-9 (compound 12c) is a potent and selective HDAC6 inhibitor with IC50 values of 11.8, 15.2, 4.2, 139.6, 21.3 nM for HDAC1,HDAC3, HDAC6, HDAC8, HDAC10, respectively. HDAC6-IN-9 shows anti-proliferative activities[1].

IC50 & Target[1]

HDAC1

11.8 nM (IC50)

HDAC3

15.2 nM (IC50)

HDAC6

4.2 nM (IC50)

HDAC8

139.6 nM (IC50)

HDAC10

21.3 nM (IC50)

Molecular Weight

320.34

Formula

C19H16N2O3
CAS No.
SMILES

O=C(NC1=CC=C2C=CC=CC2=C1)CC3=CC=C(C=C3)C(NO)=O
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HDAC6-IN-9 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HDAC6-IN-92796282-58-9HDACHistone deacetylasesA375A549MCF-7anti-proliferative4-anilinoquinazolineInhibitorinhibitorinhibit

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