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  3. Hexacyclen

Hexacyclen  (Synonyms: Hexaaza-18-crown-6; 1,4,7,10,13,16-Hexaazacyclooctadecane)

Cat. No.: HY-W034566
Handling Instructions Technical Support

Hexacyclen is an organic compound with a unique macrocyclic structure composed of six nitrogen-containing rings. It is commonly used as a chelating agent in chemistry and biochemistry due to its ability to bind metal ions. Inhibitors of certain diseases such as cancer. In biochemistry, Hexacyclen is often used to selectively bind metal ions in proteins or enzymes to study their structure and function. Due to its large size and complex structure, Hexacyclen is not widely used in daily products or applications.

For research use only. We do not sell to patients.

Hexacyclen Chemical Structure

Hexacyclen Chemical Structure

CAS No. : 296-35-5

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Other Forms of Hexacyclen:

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Description

Hexacyclen is an organic compound with a unique macrocyclic structure composed of six nitrogen-containing rings. It is commonly used as a chelating agent in chemistry and biochemistry due to its ability to bind metal ions. Inhibitors of certain diseases such as cancer. In biochemistry, Hexacyclen is often used to selectively bind metal ions in proteins or enzymes to study their structure and function. Due to its large size and complex structure, Hexacyclen is not widely used in daily products or applications[1].

In Vitro

Hexacyclen is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

258.41

Formula

C12H30N6

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

N1CCNCCNCCNCCNCCNCC1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (386.98 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.8698 mL 19.3491 mL 38.6982 mL
5 mM 0.7740 mL 3.8698 mL 7.7396 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.8698 mL 19.3491 mL 38.6982 mL 96.7455 mL
5 mM 0.7740 mL 3.8698 mL 7.7396 mL 19.3491 mL
10 mM 0.3870 mL 1.9349 mL 3.8698 mL 9.6745 mL
15 mM 0.2580 mL 1.2899 mL 2.5799 mL 6.4497 mL
20 mM 0.1935 mL 0.9675 mL 1.9349 mL 4.8373 mL
25 mM 0.1548 mL 0.7740 mL 1.5479 mL 3.8698 mL
30 mM 0.1290 mL 0.6450 mL 1.2899 mL 3.2248 mL
40 mM 0.0967 mL 0.4837 mL 0.9675 mL 2.4186 mL
50 mM 0.0774 mL 0.3870 mL 0.7740 mL 1.9349 mL
60 mM 0.0645 mL 0.3225 mL 0.6450 mL 1.6124 mL
80 mM 0.0484 mL 0.2419 mL 0.4837 mL 1.2093 mL
100 mM 0.0387 mL 0.1935 mL 0.3870 mL 0.9675 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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