HIV-1 inhibitor-53 

HIV-1 inhibitor-53 is a dual HIV-1 protease and reverse transcriptase inhibitor. HIV-1 inhibitor-53 inhibits HIV-1 protease (PR) and reverse transcriptase (RT) activity with IC₅₀ values of 1.93 nM and 2.35 μM, respectively. HIV-1 inhibitor-53 can be used for the research of acquired immune deficiency syndrome (AIDS)^[1].

IC50: 1.93 nM (protease); 2.35 μM (reverse transcriptase)^[1]

HIV-1 inhibitor-53 has inhibition against HIV-1 protease (PR) and reverse transcriptase (RT) with IC₅₀ values of 1.93 nM and 2.35 μM, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

582.66

C₃₀H₃₄N₂O₈S

2883496-10-2

COC1=CC=C(C=C1)S(=O)(N(C[C@H]([C@@H](NC(C2=CC3=C(O2)C=C(C(O)=C3)O)=O)CC4=CC=CC=C4)O)CC(C)C)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Mei Zhu, Structure based design and evaluation of benzoheterocycle derivatives as potential dual HIV-1 protease and reverse transcriptase inhibitors. Eur J Med Chem  [Content Brief]