2. MAPK/ERK Pathway
  3. MAP4K
  4. HPK1-IN-12

HPK1-IN-12 is potent inhibitor of HPK1. HPK1 is a serine/threonine protein kinase cloned from hematopoietic progenitor cells and belongs to the MAP4K family of mammalian Ste-20-related protein kinases. HPK1-IN-12 has the potential for the research of HPK1 related diseases (extracted from patent WO2021213317A1, compound 85) .

For research use only. We do not sell to patients.

HPK1-IN-12 Chemical Structure

HPK1-IN-12 Chemical Structure

CAS No. : 2734168-51-3

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HPK1-IN-12 Related Antibodies

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MAP4K2/GCK MAP4K3/GLK MAP4K4/HGK MAP4K5/KHS1 MAP4K6/MINK1 MAP4K7/TNIK MAP4K1/HPK1

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Description

HPK1-IN-12 is potent inhibitor of HPK1. HPK1 is a serine/threonine protein kinase cloned from hematopoietic progenitor cells and belongs to the MAP4K family of mammalian Ste-20-related protein kinases. HPK1-IN-12 has the potential for the research of HPK1 related diseases (extracted from patent WO2021213317A1, compound 85) [1].

Molecular Weight

445.49

Formula

C25H24FN5O2
CAS No.
SMILES

FC1=C(C2=NC3=C(C=C2)NN=C3C4=CC(OCC5N6CCN(C5)C)=C6C=C4)C(OC)=CC=C1
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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HPK1-IN-12 Related Classifications

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HPK1-IN-122734168-51-3MAP4KMAPK Kinase Kinase KinaseHPK1hematopoietic progenitor cellSte-20-related protein kinasesInhibitorinhibitorinhibit

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