1. PROTAC
  2. PROTAC Linkers
  3. Hydroxy-PEG4-CH2-Boc

Hydroxy-PEG4-CH2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Hydroxy-PEG4-CH2-Boc Chemical Structure

Hydroxy-PEG4-CH2-Boc Chemical Structure

CAS No. : 169751-72-8

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Description

Hydroxy-PEG4-CH2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

308.37

Formula

C14H28O7

CAS No.
Appearance

Liquid (Density: 1.077±0.06 g/cm3)

Color

Colorless to light yellow

SMILES

O=C(OC(C)(C)C)COCCOCCOCCOCCO

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Purity & Documentation

Purity: ≥97.0%

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Hydroxy-PEG4-CH2-Boc Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Hydroxy-PEG4-CH2-Boc
Cat. No.:
HY-42617
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