2. PROTAC
  3. PROTAC Linkers
  4. Hydroxy-PEG4-CH2-Boc

Hydroxy-PEG4-CH2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

Hydroxy-PEG4-CH2-Boc Chemical Structure

Hydroxy-PEG4-CH2-Boc Chemical Structure

CAS No. : 169751-72-8

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Based on 1 publication(s) in Google Scholar

Hydroxy-PEG4-CH2-Boc Related Antibodies

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Description

Hydroxy-PEG4-CH2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein.
PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Hydroxy-PEG4-CH2-Boc Related Antibodies
Molecular Weight

308.37

Formula

C14H28O7
CAS No.
Appearance

Liquid (Density: 1.077±0.06 g/cm3)

Color

Colorless to light yellow

SMILES

O=C(OC(C)(C)C)COCCOCCOCCOCCO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Purity & Documentation

Purity: ≥97.0%

SDS (392 KB)

COA (240 KB)

Handling Instructions (2659 KB)
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Hydroxy-PEG4-CH2-Boc Related Classifications

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hydroxy-PEG4-CH2-Boc169751-72-8PROTAC LinkerscancerprotaclinkerInhibitorinhibitorinhibit

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