Hydroxypyruvic acid lithium hydrate (Synonyms: β-Hydroxypyruvic acid lithium hydrate; 3-Hydroxypyruvic acid lithium hydrate)

Cat. No.: HY-113013A: FAQs
Data Sheet Handling Instructions

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Hydroxypyruvic acid lithium hydrate (β-Hydroxypyruvic acid lithium hydrate) is an intermediate in the metabolism of glycine, serine and threonine. Hydroxypyruvic acid lithium hydrate is a substrate for serine-pyruvate aminotransferase and glyoxylate reductase/hydroxypyruvate reductase. Hydroxypyruvic acid lithium hydrate is involved in the metabolic disorder which is the dimethylglycine dehydrogenase deficiency pathway.

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Hydroxypyruvic acid lithium hydrate Chemical Structure

CAS No. : 209728-15-4

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Other Forms of Hydroxypyruvic acid lithium hydrate:

Hydroxypyruvic acid Get quote
Hydroxypyruvic acid lithium Get quote

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Description

IC₅₀ & Target

Human Endogenous Metabolite

In Vivo

Hydroxypyruvic acid (lithium hydrate) (intravenous injection; 100 mg/ml; slowly over 10 min) increases the 5-h urinary oxalate and glycolate excretion to 0.68% (6.56 μmol) and 0.53% (5.10 μmol) in control rats, in addition, it increases to 2.43% (23.36 μmol) and 0.79% (7.59 μmol) of the dose in the vitamin-B6-deficient rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

128.01

Formula

C₃H₅LiO₅

CAS No.

209728-15-4

SMILES

O=C(O[Li])C(CO)=O.[H]O[H]

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Teerajetgul Y, et al. Oxalate synthesis from hydroxypyruvate in vitamin-B6-deficient rats.Urol Res. 2007 Aug;35(4):173-8. Epub 2007 Jun 13. [Content Brief]

Hydroxypyruvic acid lithium hydrate Related Classifications

Metabolic Disease

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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