2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Histamine Receptor
  4. Hydroxyzine-d8

Hydroxyzine-d8 is deuterium labeled Hydroxyzine. Hydroxyzine is a histamine H1-receptor antagonist[1].

For research use only. We do not sell to patients.

Hydroxyzine-d<sub>8</sub> Chemical Structure

Hydroxyzine-d8 Chemical Structure

CAS No. : 1189480-47-4

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1 mg USD 520 In-stock
5 mg USD 1800 In-stock
10 mg USD 3150 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Hydroxyzine-d8:

Hydroxyzine-d8 Related Antibodies

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H1 Receptor H2 Receptor H3 Receptor H4 Receptor Histamine Receptor

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Description

Hydroxyzine-d8 is deuterium labeled Hydroxyzine. Hydroxyzine is a histamine H1-receptor antagonist[1].

IC50 & Target

H1 Receptor

 

Molecular Weight

382.95

Formula

C21H19D8ClN2O2
CAS No.
Unlabeled CAS

68-88-2
Appearance

Solid

Color

White to off-white

SMILES

ClC1=CC=C(C(N2C([2H])([2H])C([2H])([2H])N(CCOCCO)C([2H])([2H])C2([2H])[2H])C3=CC=CC=C3)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

Ethanol : ≥ 10 mg/mL (26.11 mM)

Ethanol : ≥ 10 mg/mL (26.11 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6113 mL 13.0565 mL 26.1131 mL
5 mM 0.5223 mL 2.6113 mL 5.2226 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / Ethanol 1 mM 2.6113 mL 13.0565 mL 26.1131 mL 65.2827 mL
5 mM 0.5223 mL 2.6113 mL 5.2226 mL 13.0565 mL
10 mM 0.2611 mL 1.3057 mL 2.6113 mL 6.5283 mL
15 mM 0.1741 mL 0.8704 mL 1.7409 mL 4.3522 mL
20 mM 0.1306 mL 0.6528 mL 1.3057 mL 3.2641 mL
25 mM 0.1045 mL 0.5223 mL 1.0445 mL 2.6113 mL
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Hydroxyzine-d8 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hydroxyzine-d81189480-47-4Histamine ReceptorhistamineInhibitorinhibitorinhibit

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