Hydroxyzine-d₈

Cat. No.: HY-B0548S1 Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Hydroxyzine-d₈ is deuterium labeled Hydroxyzine. Hydroxyzine is a histamine H1-receptor antagonist[1].

For research use only. We do not sell to patients.

Hydroxyzine-d<sub>8</sub> Chemical Structure

Hydroxyzine-d₈ Chemical Structure

CAS No. : 1189480-47-4

Size	Price	Stock	Quantity
1 mg	USD 520	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 1800	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 3150	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Hydroxyzine-d₈:

Hydroxyzine In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Hydroxyzine-d₈ is deuterium labeled Hydroxyzine. Hydroxyzine is a histamine H1-receptor antagonist[1].

IC₅₀ & Target

H₁ Receptor

Molecular Weight

382.95

Formula

C₂₁H₁₉D₈ClN₂O₂

CAS No.

1189480-47-4

Unlabeled CAS

68-88-2

Appearance

Solid

Color

White to off-white

SMILES

ClC1=CC=C(C(N2C([2H])([2H])C([2H])([2H])N(CCOCCO)C([2H])([2H])C2([2H])[2H])C3=CC=CC=C3)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

Ethanol : ≥ 10 mg/mL (26.11 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.6113 mL	13.0565 mL	26.1131 mL
5 mM	0.5223 mL	2.6113 mL	5.2226 mL
10 mM	0.2611 mL	1.3057 mL	2.6113 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (271 KB) SDS (251 KB)

COA (249 KB) HNMR (117 KB) LCMS (87 KB)

Handling Instructions (2659 KB)

References

[1]. Minogiannis, P., et al., Hydroxyzine inhibits neurogenic bladder mast cell activation. Int J Immunopharmacol, 1998. 20(10): p. 553-63. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

Ethanol / Ethanol	1 mM	2.6113 mL	13.0565 mL	26.1131 mL	65.2827 mL
	5 mM	0.5223 mL	2.6113 mL	5.2226 mL	13.0565 mL
	10 mM	0.2611 mL	1.3057 mL	2.6113 mL	6.5283 mL
	15 mM	0.1741 mL	0.8704 mL	1.7409 mL	4.3522 mL
	20 mM	0.1306 mL	0.6528 mL	1.3057 mL	3.2641 mL
	25 mM	0.1045 mL	0.5223 mL	1.0445 mL	2.6113 mL