2. MAPK/ERK Pathway
  3. MAP3K
  4. IACS-52825

IACS-52825 is a potent and selective DLK inhibitor with Kd of 1.3 nM, useful for the study of chemotherapy-induced peripheral neuropathy.

For research use only. We do not sell to patients.

IACS-52825 Chemical Structure

IACS-52825 Chemical Structure

CAS No. : 2640376-72-1

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Based on 1 publication(s) in Google Scholar

IACS-52825 Related Antibodies

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MAP3K7/TAK1 MAP3K8/COT/Tpl2 MAP3K6/ASK2 MAP3K5/ASK1

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Description

IACS-52825 is a potent and selective DLK inhibitor with Kd of 1.3 nM, useful for the study of chemotherapy-induced peripheral neuropathy[1].

Molecular Weight

426.29

Formula

C16H13F7N4O2
CAS No.
SMILES

NC1=NC=C(C=C1OC(F)(F)F)C2=CN(C([C@@H](O)C(F)(F)F)=N2)C34CC(C3)(C4)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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IACS-52825 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IACS-528252640376-72-1IACS52825IACS 52825MAP3KMAP kinase kinase kinase, MEKK, MAPKKKInhibitorinhibitorinhibit

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