2. Metabolic Enzyme/Protease
  3. Indoleamine 2,3-Dioxygenase (IDO)
  4. IDO1-IN-25

IDO1-IN-25 is a dual inhibitor of IDO1/TDO2, with IC50 values of 0.17 μM and 3.2 μM, respectively. IDO1-IN-25 can effectively inhibit the production of NO in RAW264.7 cells stimulated by lipopolysaccharide (LPS). IDO1-IN-25 can exert anti-inflammatory effects in a mouse ear edema acute inflammation model induced by croton oil.

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IDO1-IN-25 Chemical Structure

IDO1-IN-25 Chemical Structure

CAS No. : 2841467-86-3

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IDO1-IN-25 Related Antibodies

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Description

IDO1-IN-25 is a dual inhibitor of IDO1/TDO2, with IC50 values of 0.17 μM and 3.2 μM, respectively. IDO1-IN-25 can effectively inhibit the production of NO in RAW264.7 cells stimulated by lipopolysaccharide (LPS). IDO1-IN-25 can exert anti-inflammatory effects in a mouse ear edema acute inflammation model induced by croton oil[1].
Molecular Weight

360.64

Formula

C14H8Cl3NO2S
CAS No.
SMILES

O=S(CC1=CC=C(Cl)C=C1)C(O2)=NC3=C2C=C(Cl)C(Cl)=C3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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IDO1-IN-25 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

IDO1-IN-252841467-86-3Indoleamine 2,3-Dioxygenase (IDO)IDO1/TDO2RAW264.7NOinflammationInhibitorinhibitorinhibit

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