1. Anti-infection
  2. Antibiotic
  3. Ikarugamycin

Ikarugamycin is an antibiotic and a inhibitor of clathrin-mediated endocytosis (CME).

For research use only. We do not sell to patients.

Ikarugamycin Chemical Structure

Ikarugamycin Chemical Structure

CAS No. : 36531-78-9

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Description

Ikarugamycin is an antibiotic and a inhibitor of clathrin-mediated endocytosis (CME)[1].

IC50 & Target

Clathrin-mediated endocytosis[1]

In Vitro

Ikarugamycin has an IC50 of 2.7 μM in H1299 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

478.62

Formula

C29H38N2O4

CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

O=C(/C=C/[C@@H]1C[C@]2([C@@]([H])([C@H]1C/C=C\3)C=C[C@@]4([C@@]2(C[C@H]([C@H]4CC)C)[H])[H])[H])C5=C([C@@H](NC5=O)CCCNC3=O)O

Structure Classification
Initial Source

Streptomyces species 

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥99.0%

References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Ikarugamycin
Cat. No.:
HY-119764
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