Imdatifan (Synonyms: HIF-2α-IN-7)

Cat. No.: HY-148264: FAQs
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Imdatifan (HIF-2α-IN-7) is a hypoxia inducible factor 2α (HIF-2α) inhibitor. Imdatifan can inhibit HIF-2α with an EC₅₀ value of 6 nM. Imdatifan can be used for the research of various types of diseases including cancer, liver disease, inflammatory disease, pulmonary diseases and iron load disorders.

For research use only. We do not sell to patients.

Imdatifan Chemical Structure

CAS No. : 2511247-29-1

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HIF-1α HIF

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Description	Imdatifan (HIF-2α-IN-7) is a hypoxia inducible factor 2α (HIF-2α) inhibitor. Imdatifan can inhibit HIF-2α with an EC₅₀ value of 6 nM. Imdatifan can be used for the research of various types of diseases including cancer, liver disease, inflammatory disease, pulmonary diseases and iron load disorders^[1].
IC₅₀ & Target	EC50: 6nM (HIF-2α)^[1]
In Vitro	Imdatifan has inhibitory activity for HIF-2α with an EC₅₀ value of 6nM^[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Imdatifan Related Antibodies
Molecular Weight	385.26
Formula	C₁₈H₉F₆NO₂
CAS No.	2511247-29-1
SMILES	O[C@]12C3=C(C(F)(C1(F)F)F)C=CC(OC4=CC(C#N)=CC(F)=C4)=C3[C@H](C2)F
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (269 KB) Handling Instructions (2659 KB)
References	[1]. Jiping Fu, et al. Tetrahydro-1h-cyclopenta[cd]indene derivatives as hypoxia inducible factor-2(alpha) inhibitors. Patent. WO2020214853A1.

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	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Imdatifan2511247-29-1HIF-2α-IN-7HIF/HIF Prolyl-HydroxylaseHypoxia-inducible factorsHIFsHIF-PHhypoxia inducible factor 2α (HIF-2α)inhibitorycancerliver diseaseinflammatorypulmonaryiron load disordersInhibitorinhibitorinhibit

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Imdatifan (Synonyms: HIF-2α-IN-7)

Imdatifan Related Antibodies

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