2. Metabolic Enzyme/Protease
  3. HIF/HIF Prolyl-Hydroxylase
  4. Imdatifan

Imdatifan (HIF-2α-IN-7) is a hypoxia inducible factor 2α (HIF-2α) inhibitor. Imdatifan can inhibit HIF-2α with an EC50 value of 6 nM. Imdatifan can be used for the research of various types of diseases including cancer, liver disease, inflammatory disease, pulmonary diseases and iron load disorders.

For research use only. We do not sell to patients.

Imdatifan Chemical Structure

Imdatifan Chemical Structure

CAS No. : 2511247-29-1

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Imdatifan Related Antibodies

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HIF-1α HIF

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Description

Imdatifan (HIF-2α-IN-7) is a hypoxia inducible factor 2α (HIF-2α) inhibitor. Imdatifan can inhibit HIF-2α with an EC50 value of 6 nM. Imdatifan can be used for the research of various types of diseases including cancer, liver disease, inflammatory disease, pulmonary diseases and iron load disorders[1].

IC50 & Target

EC50: 6nM (HIF-2α)[1]
In Vitro

Imdatifan has inhibitory activity for HIF-2α with an EC50 value of 6nM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Imdatifan Related Antibodies
Molecular Weight

385.26

Formula

C18H9F6NO2
CAS No.
SMILES

O[C@]12C3=C(C(F)(C1(F)F)F)C=CC(OC4=CC(C#N)=CC(F)=C4)=C3[C@H](C2)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Imdatifan Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Imdatifan2511247-29-1HIF-2α-IN-7HIF/HIF Prolyl-HydroxylaseHypoxia-inducible factorsHIFsHIF-PHhypoxia inducible factor 2α (HIF-2α)inhibitorycancerliver diseaseinflammatorypulmonaryiron load disordersInhibitorinhibitorinhibit

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