2. Anti-infection
  3. Influenza Virus
  4. Influenza virus-IN-2

Influenza virus-IN-2 (compound 19) is a potent influenza virus inhibitor with an EC50 of 2.58 µM and CC50 of 150.85 µM. Influenza virus-IN-2 shows a concentration dependent inhibition activity for PAN endonuclease with EC50 of 489.39 nM. Influenza virus-IN-2 shows shows anti-influenza A virus activities.

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Influenza virus-IN-2 Chemical Structure

Influenza virus-IN-2 Chemical Structure

CAS No. : 2411584-06-8

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Influenza virus-IN-2 Related Antibodies

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Description

Influenza virus-IN-2 (compound 19) is a potent influenza virus inhibitor with an EC50 of 2.58 µM and CC50 of 150.85 µM. Influenza virus-IN-2 shows a concentration dependent inhibition activity for PAN endonuclease with EC50 of 489.39 nM. Influenza virus-IN-2 shows shows anti-influenza A virus activities[1].

IC50 & Target

EC50: 2.58 µM (influenza virus); CC50: 150.85 µM (influenza virus)[1]
Cellular Effect
Cell Line Type Value Description References
MDCK CC50
150.85 μM
Compound: 19
Cytotoxicity against dog MDCK cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against dog MDCK cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
[PMID: 31954881]
Molecular Weight

315.32

Formula

C17H17NO5
CAS No.
SMILES

OC1=CC=C(CC(N2CC3=C(C=C(O)C(O)=C3)CC2)=O)C=C1O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Influenza virus-IN-2 Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Influenza virus-IN-22411584-06-8Influenza VirusMDCK cellsanti-IAV activityPAN endonucleaseInhibitorinhibitorinhibit

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