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  4. Insulin icodec

Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec can be used for the research of type 2 diabetes.

For research use only. We do not sell to patients.

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Insulin icodec Chemical Structure

Insulin icodec Chemical Structure

CAS No. : 1188379-43-2

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Description

Insulin icodec is an Insulin (HY-P0035) analog that strongly but reversibly binds to albumin. Insulin icodec has long plasma half-life. Insulin icodec can be used for the research of type 2 diabetes[1].

Molecular Weight

6380.26

Formula

C280H435N71O87S6

CAS No.
Sequence

Chain1:Phe-Val-Asn-Gln-His-Leu-Cys-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-His-Leu-Val-Cys-Gly-Glu-Arg-Gly-Phe-His-Tyr-Thr-Pro-{Lys(2OEG-γGlu-C20 diacid)} Chain2:Phe-Val-Asn-Gln-His-Leu-Cys-Gly-Ser-His-Leu-Val-Glu-Ala-Leu-His-Leu-Val-Cys-Gly-Glu-Arg-Gly-Phe-His-Tyr-Thr-Pro-Lys Chain3: {Ggu}-{Oaa}-{Oaa}(Disulfide: chain 1 cys7-chain 2 cys7, Disulfide: chain 1 cys19-chain 2 cys20, Disulfide: chain 2 cys6-cys11, amide chain 1 lysine-29 to chain 3 ω-amino acid-3)

Sequence Shortening

Chain1: FVNQHLCGSHLVEALHLVCGERGFHYTP-{Lys(2OEG-γGlu-C20 diacid)};Chain2: GIVEQCCTSICSLEQLENYCN;Chain3: {Ggu}-{Oaa}-{Oaa} (Disulfide: chain 1 cys7-chain 2 cys7, Disulfide: chain 1 cys19-chain 2 cys20, Disulfide: chain 2 cys6-cys11, amide chain 1 lysine-29 to chain 3 ω-amino acid-3)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Insulin icodec
Cat. No.:
HY-P4070
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