1. Immunology/Inflammation Vitamin D Related/Nuclear Receptor
  2. Glucocorticoid Receptor
  3. IONIS-GCCRRx

IONIS-GCCRRx (ISIS 426115), a glucocorticoid receptor antagonist, is a 2'-O-methoxyethyl (2'-MOE) antisense oligonucleotide (ASO).

For research use only. We do not sell to patients.

DNA, d(P-thio)([2'-O-(2-methoxyethyl)]rG-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]rA-[2'-O-(2-methoxyethyl)]rG-[2'-O-(2-methoxyethyl)]m5rC-m5C-A-T-G-G-T-G-A-T-m5C-[2'-O-(2-methoxyethyl)]rA-[2'-O-(2-methoxyethyl)]rG-[2'-O-(2-methoxyethyl)]rG-[2'-O-(2-methoxyethyl)]rA-[2'-O-(2-methoxyethyl)]rG)

IONIS-GCCRRx Chemical Structure

CAS No. : 1431900-72-9

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Description

IONIS-GCCRRx (ISIS 426115), a glucocorticoid receptor antagonist, is a 2'-O-methoxyethyl (2'-MOE) antisense oligonucleotide (ASO)[1].

CAS No.
SMILES

[IONIS-GCCRRx]

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
IONIS-GCCRRx
Cat. No.:
HY-159695
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