Isoarundinin I

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Isoarundinin I is a stilbene compound that can be isolated from Arundinu bambusifolia.

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Isoarundinin I Chemical Structure

CAS No. : 151538-57-7

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nNOS iNOS eNOS

Biological Activity
Purity & Documentation
References
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Description

Isoarundinin I is a stilbene compound that can be isolated from Arundinu bambusifolia^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
ADR5000 cell line	IC₅₀	60.42 μM Compound: 1	Cytotoxicity against human CEM/ADR5000 cells overexpressing P-gp assessed as inhibition of cell growth incubated for 72 hrs by resazurin assay Cytotoxicity against human CEM/ADR5000 cells overexpressing P-gp assessed as inhibition of cell growth incubated for 72 hrs by resazurin assay	[PMID: 36538372]
CCRF-CEM	IC₅₀	43.36 μM Compound: 1	Cytotoxicity against human CCRF-CEM cells assessed as inhibition of cell growth incubated for 72 hrs by resazurin assay Cytotoxicity against human CCRF-CEM cells assessed as inhibition of cell growth incubated for 72 hrs by resazurin assay	[PMID: 36538372]
Neutrophil	IC₅₀	1.7 μM Compound: 34	Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/cytochalasin B-induced superoxide anion generation by measuring superoxide dismutase-inhibitable reduction of ferricytochrome c preincubated for 5 mins followed by FMLP/cytochal Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/cytochalasin B-induced superoxide anion generation by measuring superoxide dismutase-inhibitable reduction of ferricytochrome c preincubated for 5 mins followed by FMLP/cytochal	[PMID: 27525452]
Neutrophil	IC₅₀	2.8 μM Compound: 34	Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate preincubated for 5 mins followed by fMLP/CB-induction Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate preincubated for 5 mins followed by fMLP/CB-induction	[PMID: 27525452]

Molecular Weight

350.41

Formula

C₂₂H₂₂O₄

CAS No.

151538-57-7

SMILES

OC1=CC=C(CC2=C(CCC3=CC(O)=CC=C3)C=C(O)C=C2OC)C=C1

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. P.L. Majumder, et al. Two stilbenoids from the orchid arundina bambusifolia. Phytochemistry. 1993, 35, 1.

[2]. Majumder P L, Ghosal S. Two stilbenoids from the orchid Arundina bambusifolia[J]. Phytochemistry, 1993, 32(2): 439-444.

[3]. Yuan Li, et al. Nitrogen-containing bibenzyls from Pleione bulbocodioides: absolute configurations and biological activities. Fitoterapia. 2015. [Content Brief]

Isoarundinin I Related Classifications

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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Isoarundinin I151538-57-7NO SynthaseNitric oxide synthasesNOSnatural productInhibitorinhibitorinhibit

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