2. Apoptosis
  3. Apoptosis
  4. Isodispar B

Isodispar B is an anticancer agent that inhibits the proliferation of nasopharyngeal carcinoma and breast cancer cells and induces cell apoptosis. Isodispar B is cytotoxic to a wide range of cancer cell lines.

For research use only. We do not sell to patients.

Isodispar B Chemical Structure

Isodispar B Chemical Structure

CAS No. : 98192-64-4

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Isodispar B Related Antibodies

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Description

Isodispar B is an anticancer agent that inhibits the proliferation of nasopharyngeal carcinoma and breast cancer cells and induces cell apoptosis. Isodispar B is cytotoxic to a wide range of cancer cell lines[1].

In Vitro

Isodispar B (compound 1) (0-100 μM; 72 h) exerts a broad spectrum of anti-cancer activity to inhibit cell proliferation with IC50s of 3.84-56.73 μM[1].
Isodispar B (1 μM and 10 μM; 3 d) induces apoptosis on nasopharyngeal cancer cells (TW01, CNE1, HK1, and SUNE1)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Isodispar B Related Antibodies

Cell Cytotoxicity Assay[1]

Cell Line: Nasopharyngeal cancer cells (TW01, CNE1, HK1, and SUNE1) and noncancerous nasopharyngeal cells (NP460)
Concentration: 0-100 μM
Incubation Time: 72 hours
Result: Showed cytotoxicity and inhibited cell viability with IC50s of 3.84 μM (SUNE1), 11.49 μM (TW01), 9.74 μM (CNE1), 5.58 μM (HK1), 56.73 μM (HCC38), 52.69 μM (MDA-MB-231), 52.75 μM (MDA-ME-468), and 54.85 μM (SKBR3), respectively.
Molecular Weight

338.35

Formula

C20H18O5
CAS No.
SMILES

O=C1C=C(C2=CC=CC=C2)C3=C(O)C=C(O)C(C(CC(C)C)=O)=C3O1
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Isodispar B Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Isodispar B98192-64-4ApoptosisInhibitorinhibitorinhibit

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