Jacareubin

Cat. No.: HY-114716: FAQs
Data Sheet Handling Instructions

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Jacareubin is a xanthone compound that can be isolated from Calophyllum brasiliense. Jacareubin has antibacterial, antioxidant, gastroprotective properties, and also has certain cancer cell toxicity, which can be used in cancer research.

For research use only. We do not sell to patients.

Jacareubin Chemical Structure

CAS No. : 3811-29-8

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Biological Activity
Purity & Documentation
References
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Description

Cellular Effect

Cell Line	Type	Value	Description	References
HeLa	IC₅₀	4.8 μM Compound: 16	Antiproliferative activity against human HeLa cells after 48 hrs by CCK8 assay Antiproliferative activity against human HeLa cells after 48 hrs by CCK8 assay	[PMID: 29475587]
HL-60	IC₅₀	1 μM Compound: 16	Antiproliferative activity against human HL60 cells after 48 hrs by CCK8 assay Antiproliferative activity against human HL60 cells after 48 hrs by CCK8 assay	[PMID: 29475587]
NIH3T3	CC₅₀	10.2 μM Compound: 16	Cytotoxicity against mouse NIH/3T3 cells after 48 hrs by CCK8 assay Cytotoxicity against mouse NIH/3T3 cells after 48 hrs by CCK8 assay	[PMID: 29475587]

Molecular Weight

326.30

Formula

C₁₈H₁₄O₆

CAS No.

3811-29-8

SMILES

O=C1C2=C(C=C3C(C=CC(C)(O3)C)=C2O)OC4=C1C=CC(O)=C4O

Structure Classification

Flavonoids

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. W R García-Niño, et al. Cytogenetic effects of Jacareubin from Calophyllum brasiliense on human peripheral blood mononucleated cells in vitro and on mouse polychromatic erythrocytes in vivo. Toxicol Appl Pharmacol. 2017 Nov 15;335:6-15. [Content Brief]

Jacareubin Related Classifications

Molarity Calculator
Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Jacareubin3811-29-8BacterialReactive Oxygen SpeciesInhibitorinhibitorinhibit

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