JTP10-△-TATi TFA 

JTP10-△-TATi TFA is a selective JNK2 peptide inhibitor, with an IC₅₀ of 92 nM, exhibiting 10-fold selectivity for JNK2 over JNK1 and JNK3^[1].

JTP10-△-TATi TFA inhibits the migration of PyVMTjnk^2+/+ cells and PyVMTjnk^2-/- cells expressing GFP-JNK2α^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

2833.28

C₁₂₀H₂₁₃F₃N₄₈O₂₈

Solid

White to off-white

Ac-PKRPTTLNLF-{Ahx}-RRRQRRKKRG-NH2

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture and light, under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

• [1]. Tamer S. Kao, et al. Development of JNK2-selective peptide inhibitors that inhibit breast cancer cell migration. ACS Chem Biol. 2011 Jun 17;6(6):658-66.  [Content Brief]