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Juncusol, a phenanthrenoid found in Juncus setchuenensis, possesses anxiolytic effect. Juncusol is associated with metabolic changes in cortical serotonin/dopamine levels in Mice.

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Juncusol Chemical Structure

Juncusol Chemical Structure

CAS No. : 62023-90-9

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Based on 1 publication(s) in Google Scholar

Juncusol Related Antibodies

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Description

Juncusol, a phenanthrenoid found in Juncus setchuenensis, possesses anxiolytic effect. Juncusol is associated with metabolic changes in cortical serotonin/dopamine levels in Mice[1].
Cellular Effect
Cell Line Type Value Description References
HEK293 IC50
6.5 μM
Compound: 8
Inhibition of OAT3 (unknown origin) expressed in HEK293 cells assessed as reduction in 6-CF uptake measured after 5 mins by fluorescence assay
Inhibition of OAT3 (unknown origin) expressed in HEK293 cells assessed as reduction in 6-CF uptake measured after 5 mins by fluorescence assay
[PMID: 30892891]
RAW264.7 IC50
3.1 μM
Compound: Juncusol
Antiinflammatory activity in mouse RAW 264.7 cells assessed as inhibition of LPS-induced nitric oxide production measured after 48 hrs by Griess reagent assay
Antiinflammatory activity in mouse RAW 264.7 cells assessed as inhibition of LPS-induced nitric oxide production measured after 48 hrs by Griess reagent assay
[PMID: 29280630]
Molecular Weight

266.33

Formula

C18H18O2
CAS No.
SMILES

OC(C(C)=C1CC2)=CC=C1C3=C2C=C(O)C(C)=C3C=C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Juncusol Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Juncusol62023-90-9OthersInhibitorinhibitorinhibit

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