2. GPCR/G Protein MAPK/ERK Pathway Apoptosis
  3. Ras Apoptosis
  4. KRAS G12C inhibitor 63

KRAS G12C inhibitor 63 (K45) is a KRAS G12C inhibitor. KRAS G12C inhibitor 63 can induce Apoptosis. KRAS G12C inhibitor 63 has antitumor activity.

For research use only. We do not sell to patients.

KRAS G12C inhibitor 63 Chemical Structure

KRAS G12C inhibitor 63 Chemical Structure

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KRAS G12C inhibitor 63 Related Antibodies

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Description

KRAS G12C inhibitor 63 (K45) is a KRAS G12C inhibitor. KRAS G12C inhibitor 63 can induce Apoptosis. KRAS G12C inhibitor 63 has antitumor activity[1].

In Vitro

KRAS G12C inhibitor 63 shows strong anti-proliferation ability against KRAS-G12C-carrying NCI-H23 and NCI-H358 cancer cells, IC50 values are 0.77 μM and 1.50 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

KRAS G12C inhibitor 63 Related Antibodies
Molecular Weight

511.40

Formula

C27H24Cl2N2O4
SMILES

COC1=CC(C2=C(Cl)C=C3C(OC(C=C3N4CCN(C(CCl)=O)[C@H](C)C4)=O)=C2)=C5C=CC=CC5=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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KRAS G12C inhibitor 63 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

KRAS G12C inhibitor 63RasApoptosisKRAS-G12CInhibitorNCI-H23NCI-H358inhibitorinhibit

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KRAS G12C inhibitor 63
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