2. GPCR/G Protein
  3. LPL Receptor
  4. L-threo Lysosphingomyelin (d18:1)

L-threo Lysosphingomyelin (d18:1)  (Synonyms: L-threo-Sphingosylphosphorylcholine)

Cat. No.: HY-113934 Purity: ≥98.0%
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L-threo Lysosphingomyelin (d18:1) (L-threo-Sphingosylphosphorylcholine) is an endogenous bioactive sphingolipid. L-threo Lysosphingomyelin (d18:1) is a potent S1P receptor agonist with EC50s of 19.3, 131.8, and 313.3 nM for hS1P1, hS1P3, and hS1P2, respectively.

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L-threo Lysosphingomyelin (d18:1) Chemical Structure

L-threo Lysosphingomyelin (d18:1) Chemical Structure

CAS No. : 105615-55-2

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Based on 1 publication(s) in Google Scholar

L-threo Lysosphingomyelin (d18:1) Related Antibodies

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Description

L-threo Lysosphingomyelin (d18:1) (L-threo-Sphingosylphosphorylcholine) is an endogenous bioactive sphingolipid. L-threo Lysosphingomyelin (d18:1) is a potent S1P receptor agonist with EC50s of 19.3, 131.8, and 313.3 nM for hS1P1, hS1P3, and hS1P2, respectively[1].

IC50 & Target[1]

S1PR1

19.3 nM (EC50, human)

S1PR3

131.8 nM (EC50, human)

S1PR2

313.3 nM (EC50, human)

Molecular Weight

464.62

Formula

C23H49N2O5P
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=P(OCC[N+](C)(C)C)(OC[C@H](N)[C@@H](O)/C=C/CCCCCCCCCCCCC)[O-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥98.0%

COA (240 KB)

Handling Instructions (2659 KB)
References
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L-threo Lysosphingomyelin (d18:1) Related Classifications

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Keywords:

L-threo Lysosphingomyelin (d18:1)105615-55-2L-threo-SphingosylphosphorylcholineLPL ReceptorLysophospholipid Receptorendogenousbioactive sphingolipiddiastereoisomersphingosylphosphorylcholineInhibitorinhibitorinhibit

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