2. Anti-infection
  3. Virus Protease Flavivirus
  4. LabMol-301

LabMol-301 inhibits both NS5 RdRp and NS2B-NS3pro activity (IC50: 0.8 and 7.4 μM, respectively). LabMol-301 has a cytoprotective effect and prevents Zika virus (ZIKV)-induced cell death.

For research use only. We do not sell to patients.

LabMol-301 Chemical Structure

LabMol-301 Chemical Structure

CAS No. : 1360243-08-8

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LabMol-301 Related Antibodies

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Description

LabMol-301 inhibits both NS5 RdRp and NS2B-NS3pro activity (IC50: 0.8 and 7.4 μM, respectively). LabMol-301 has a cytoprotective effect and prevents Zika virus (ZIKV)-induced cell death[1].

IC50 & Target

NS5 RdRp, NS2B-NS3pro[1]
In Vitro

LabMol-301 (20 μM) shows 99% inhibition rate of NS5 RdRp activity[1].
LabMol-301 (10 μM) inhibits more than 80% of the NS2B-NS3pro protease activity[1].
LabMol-301 interacts with ZIKV NS2B-NS3pro at the allosteric site relied on a highly hydrophobic complementarity between the molecule’s surfaces and the protein[1].
LabMol-301 is able to protect GSC387 cell from cell death induced by ZIKV (EC50: 6.68 μM)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

LabMol-301 Related Antibodies
Molecular Weight

316.36

Formula

C18H16N6
CAS No.
SMILES

NC1=C(C2=C3C(NC=C3)=NC(NCC4=CC=CN=C4)=C2)C=NC=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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LabMol-301 Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LabMol-3011360243-08-8LabMol301LabMol 301Virus ProteaseFlavivirusZIKVZika virusNS5 RdRpNS2B-NS3proGSC387Inhibitorinhibitorinhibit

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