Liraglutide-¹³C₅,¹⁵N TFA

Name: Liraglutide- 13 C 5 , 15 N TFA
Brand: MedChemExpress
SKU: HY-P0014S1
Rating: 4.5 (1 reviews)

Cat. No.: HY-P0014S1 Purity: 98.19%: Data Sheet
SDS

COA
Handling Instructions Technical Support

Solubility

In Vivo Dissolution Calculator

Liraglutide-¹³C₅,¹⁵N (tetraTFA) is the ¹³C and ¹⁵N labeled Liraglutide (HY-P0014). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus.

For research use only. We do not sell to patients.

Liraglutide-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N TFA Chemical Structure

Liraglutide-¹³C₅,¹⁵N TFA Chemical Structure

Size	Price	Stock	Quantity
1 mg	USD 204	In-stock	Estimated Time of Arrival: April 9
5 mg	USD 510	In-stock	Estimated Time of Arrival: April 9
10 mg	USD 820	In-stock	Estimated Time of Arrival: April 9
50 mg		Get quote
100 mg		Get quote

Get it by April 15 for select sizes. Order within 9 hrs 11 mins.

or Bulk Inquiry

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Liraglutide-¹³C₅,¹⁵N TFA:

Liraglutide In-stock

Featured Recommendations

•Related Small Molecules:

Biological Activity
Purity & Documentation
References
Customer Review

Description

Liraglutide-¹³C₅,¹⁵N (tetraTFA) is the ¹³C and ¹⁵N labeled Liraglutide (HY-P0014)^[1]. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus^[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

3757.16 (free acid)

Formula

C₁₆₇¹³C₅H₂₆₅N₄₂¹⁵NO₅₁._xC₂HF₃O₂

Unlabeled CAS

204656-20-2

Appearance

Solid

Color

White to off-white

Sequence

His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-{Val-13C5,15N}-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-{Lys-N6-[N-(1-oxohexadecyl)-L-g-glutamyl]}-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly (TFA salt)

Sequence Shortening

HAEGTFTSD-{Val-13C5,15N}-SSYLGQAA-{Lys-N6-[N-(1-oxohexadecyl)-L-g-glutamyl]}-EFIAWLVRGRG (TFA salt)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 1 mg/mL (adjust pH to 10 with NH3·H2O)

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Purity & Documentation

Purity: 98.19%

Select Batch:

Data Sheet (268 KB) SDS (252 KB)

COA (244 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]