Liraglutide-¹³C₅,¹⁵N TFA

Name: Liraglutide- 13 C 5 , 15 N TFA
Brand: MedChemExpress
SKU: HY-P0014S1
Rating: 4.5 (1 reviews)

Cat. No.: HY-P0014S1 Purity: 98.19%: FAQs
Data Sheet
SDS

COA
Handling Instructions Technical Support

Liraglutide-¹³C₅,¹⁵N (tetraTFA) is the ¹³C and ¹⁵N labeled Liraglutide (HY-P0014). Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus.

For research use only. We do not sell to patients.

Liraglutide-<sup>13</sup>C<sub>5</sub>,<sup>15</sup>N TFA Chemical Structure

Liraglutide-¹³C₅,¹⁵N TFA Chemical Structure

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Liraglutide-¹³C₅,¹⁵N TFA:

Liraglutide In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Liraglutide-¹³C₅,¹⁵N (tetraTFA) is the ¹³C and ¹⁵N labeled Liraglutide (HY-P0014)^[1]. Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist used clinically to treat type 2 diabetes mellitus^[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

3757.16 (free acid)

Formula

C₁₆₇¹³C₅H₂₆₅N₄₂¹⁵NO₅₁._xC₂HF₃O₂

Unlabeled CAS

204656-20-2

Appearance

Solid

Color

White to off-white

Sequence

His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-{Val-13C5,15N}-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-{Lys-N6-[N-(1-oxohexadecyl)-L-g-glutamyl]}-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly (TFA salt)

Sequence Shortening

HAEGTFTSD-{Val-13C5,15N}-SSYLGQAA-{Lys-N6-[N-(1-oxohexadecyl)-L-g-glutamyl]}-EFIAWLVRGRG (TFA salt)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : 1 mg/mL (adjust pH to 10 with NH3·H2O)

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.19%

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Data Sheet (268 KB) SDS (252 KB)

COA (244 KB) LCMS (92 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]