1. Protein Tyrosine Kinase/RTK
  2. VEGFR
  3. Low molecular weight protamine

Low molecular weight protamine  (Synonyms: LMWP)

Cat. No.: HY-P5107 Purity: 98.03%
SDS COA Handling Instructions

Low molecular weight protamine is a cell-penetrating peptide with vascular endothelial growth factor (VEGF) inhibitory activity. Low molecular weight protamine can inhibit tumor growth and is used in cancer research.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Low molecular weight protamine Chemical Structure

Low molecular weight protamine Chemical Structure

CAS No. : 121052-30-0

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Description

Low molecular weight protamine is a cell-penetrating peptide with vascular endothelial growth factor (VEGF) inhibitory activity. Low molecular weight protamine can inhibit tumor growth and is used in cancer research[1].

Molecular Weight

1880.18

Formula

C72H142N44O16

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Val-Ser-Arg-Arg-Arg-Arg-Arg-Arg-Gly-Gly-Arg-Arg-Arg-Arg

Sequence Shortening

VSRRRRRRGGRRRR

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (53.19 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.5319 mL 2.6593 mL 5.3186 mL
5 mM 0.1064 mL 0.5319 mL 1.0637 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.5319 mL 2.6593 mL 5.3186 mL 13.2966 mL
5 mM 0.1064 mL 0.5319 mL 1.0637 mL 2.6593 mL
10 mM 0.0532 mL 0.2659 mL 0.5319 mL 1.3297 mL
15 mM 0.0355 mL 0.1773 mL 0.3546 mL 0.8864 mL
20 mM 0.0266 mL 0.1330 mL 0.2659 mL 0.6648 mL
25 mM 0.0213 mL 0.1064 mL 0.2127 mL 0.5319 mL
30 mM 0.0177 mL 0.0886 mL 0.1773 mL 0.4432 mL
40 mM 0.0133 mL 0.0665 mL 0.1330 mL 0.3324 mL
50 mM 0.0106 mL 0.0532 mL 0.1064 mL 0.2659 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Low molecular weight protamine
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