Low molecular weight protamine (Synonyms: LMWP)

Cat. No.: HY-P5107 Purity: 98.03%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

Low molecular weight protamine is a cell-penetrating peptide with vascular endothelial growth factor (VEGF) inhibitory activity. Low molecular weight protamine can inhibit tumor growth and is used in cancer research.

For research use only. We do not sell to patients.

Low molecular weight protamine Chemical Structure

CAS No. : 121052-30-0

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

1880.18

Formula

C₇₂H₁₄₂N₄₄O₁₆

CAS No.

121052-30-0

Appearance

Solid

Color

White to off-white

Sequence

Val-Ser-Arg-Arg-Arg-Arg-Arg-Arg-Gly-Gly-Arg-Arg-Arg-Arg

Sequence Shortening

VSRRRRRRGGRRRR

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (53.19 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	0.5319 mL	2.6593 mL	5.3186 mL
5 mM	0.1064 mL	0.5319 mL	1.0637 mL
10 mM	0.0532 mL	0.2659 mL	0.5319 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.03%

Select Batch:

Data Sheet (272 KB) SDS (252 KB)

COA (249 KB) RP-HPLC (206 KB)

Handling Instructions (2659 KB)

References

[1]. Choi YS, et al. The systemic delivery of siRNAs by a cell penetrating peptide, low molecular weight protamine. Biomaterials. 2010 Feb;31(6):1429-43. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	0.5319 mL	2.6593 mL	5.3186 mL	13.2966 mL
	5 mM	0.1064 mL	0.5319 mL	1.0637 mL	2.6593 mL
	10 mM	0.0532 mL	0.2659 mL	0.5319 mL	1.3297 mL
	15 mM	0.0355 mL	0.1773 mL	0.3546 mL	0.8864 mL
	20 mM	0.0266 mL	0.1330 mL	0.2659 mL	0.6648 mL
	25 mM	0.0213 mL	0.1064 mL	0.2127 mL	0.5319 mL
	30 mM	0.0177 mL	0.0886 mL	0.1773 mL	0.4432 mL
	40 mM	0.0133 mL	0.0665 mL	0.1330 mL	0.3324 mL
	50 mM	0.0106 mL	0.0532 mL	0.1064 mL	0.2659 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Low molecular weight protamine Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Low molecular weight protamine121052-30-0LMWPVEGFRVascular endothelial growth factor receptorVEGF inhibitorcell penetrating peptideCancerInhibitorinhibitorinhibit

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