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  4. Lu AF11205

Lu AF11205 is a mGlu5 receptor positive allosteric modulator with activity modulating mGlu5 receptor activity. Optimization of Lu AF11205 resulted in a series of potent fused thiazole analogs whose structures and activities were influenced by substituents and which could affect receptor function in cell lines expressing mGlu5 receptors.

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Lu AF11205 Chemical Structure

Lu AF11205 Chemical Structure

CAS No. : 1290133-16-2

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Lu AF11205 Related Antibodies

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Description

Lu AF11205 is a mGlu5 receptor positive allosteric modulator with activity modulating mGlu5 receptor activity. Optimization of Lu AF11205 resulted in a series of potent fused thiazole analogs whose structures and activities were influenced by substituents and which could affect receptor function in cell lines expressing mGlu5 receptors.

Molecular Weight

296.39

Formula

C17H16N2OS
CAS No.
SMILES

O=C(N1CCCCC1)C2=CN=C(S2)C#CC3=CC=CC=C3
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Lu AF11205 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lu AF112051290133-16-2Lu AF 11205Lu AF-11205OthersInhibitorinhibitorinhibit

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Lu AF11205
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HY-117697
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