2. Epigenetics TGF-beta/Smad
  3. PKC
  4. LY 379196

LY 379196 is a PKC-β inhibitor (IC50: 50 nM and 30 nM for PKC βI and βII respectively). LY 379196 inhibits the VEGF, IGF-1 and bFGF-induced proliferation of bovine retinal microvascular endothelial cells (BREC). LY 379196 is an antiproliferatory agentfor proliferative retinopathy.

For research use only. We do not sell to patients.

LY 379196 Chemical Structure

LY 379196 Chemical Structure

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LY 379196 Related Antibodies

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Description

LY 379196 is a PKC-β inhibitor (IC50: 50 nM and 30 nM for PKC βI and βII respectively). LY 379196 inhibits the VEGF, IGF-1 and bFGF-induced proliferation of bovine retinal microvascular endothelial cells (BREC). LY 379196 is an antiproliferatory agentfor proliferative retinopathy[1][2].

Molecular Weight

562.68

Formula

C30H34N4O5S
SMILES

O=C1NC(C2=C1C(C3=CC=CC=C34)=CN4CCC[C@H](CN(C)C)CCN5C6=CC=CC=C6C2=C5)=O.O=S(O)(C)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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LY 379196 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LY 379196LY379196LY-379196PKCProtein kinase CInhibitorinhibitorinhibit

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