2. PI3K/Akt/mTOR
  3. mTOR
  4. mTOR inhibitor-2

mTOR inhibitor-2 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR inhibitor-2 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates.

For research use only. We do not sell to patients.

mTOR inhibitor-2 Chemical Structure

mTOR inhibitor-2 Chemical Structure

CAS No. : 2219323-96-1

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mTOR inhibitor-2 Related Antibodies

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Description

mTOR inhibitor-2 is a highlt potent, selective and oral mTOR inhibitor with an IC50 of 7 nM. mTOR inhibitor-2 inhibits cellular phosphorylation of mTORC1 (pS6 and p4E-BP1) and mTORC2 (pAKT (S473)) substrates[1].

IC50 & Target

mTOR

7 nM (IC50)

Molecular Weight

411.46

Formula

C23H21N7O
CAS No.
SMILES

O=C(N1C2CCN(CC#N)CC2)C=NC3=C1C4=CC(C5=CN=C(N)C=C5)=CC=C4N=C3
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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mTOR inhibitor-2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

mTOR inhibitor-22219323-96-1mTOR inhibitor2mTOR inhibitor 2mTORMammalian target of RapamycinInhibitorinhibitorinhibit

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