2. Antibody-drug Conjugate/ADC Related
  3. Drug-Linker Conjugates for ADC
  4. MA-PEG4-VC-PAB-DMEA-duocarmycin DM

MA-PEG4-VC-PAB-DMEA-duocarmycin DM 

Cat. No.: HY-157465 Purity: 99.84%
SDS COA Handling Instructions

Molarity Calculator

MA-PEG4-VC-PAB-DMEA-duocarmycin DM is a drug-linker conjugate for ADC by using the DNA minor-groove alkylator Duocarmycin DM (HY-130978), linked via MA-PEG4-vc-PAB-DMEA (HY-126668).

For research use only. We do not sell to patients.

MA-PEG4-VC-PAB-DMEA-duocarmycin DM Chemical Structure

MA-PEG4-VC-PAB-DMEA-duocarmycin DM Chemical Structure

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1 mg USD 1043 In-stock
5 mg USD 2400 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of MA-PEG4-VC-PAB-DMEA-duocarmycin DM:

MA-PEG4-VC-PAB-DMEA-duocarmycin DM Related Antibodies

Top Publications Citing Use of Products

View All Drug-Linker Conjugates for ADC Isoform Specific Products:

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Auristatin Camptothecins Daunorubicins/Doxorubicins Duocarmycins Maytansinoids Pyrrolobenzodiazepines Traditional Cytotoxic Agents

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Description

MA-PEG4-VC-PAB-DMEA-duocarmycin DM is a drug-linker conjugate for ADC by using the DNA minor-groove alkylator Duocarmycin DM (HY-130978), linked via MA-PEG4-vc-PAB-DMEA (HY-126668).

IC50 & Target[1]

Traditional Cytotoxic Agents

 

Molecular Weight

1381.96

Formula

C68H89ClN12O17
Appearance

Solid

Color

White to off-white

SMILES

O=C(NCCOCCOCCOCCOCCC(N[C@H](C(N[C@H](C(NC1=CC=C(COC(N(CCN(C(OC2=CC3=C([C@@H](CN3C(C4=CC5=CC(OCCN(C)C)=CC=C5N4)=O)CCl)C6=CC=CC=C26)=O)C)C)=O)C=C1)=O)CCCNC(N)=O)=O)C(C)C)=O)CCN7C(C=CC7=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Purity & Documentation

Purity: 99.84%

SDS (251 KB)

COA (247 KB) HNMR (509 KB) RP-HPLC (1597 KB)

Handling Instructions (2659 KB)
References
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MA-PEG4-VC-PAB-DMEA-duocarmycin DM Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MA-PEG4-VC-PAB-DMEA-duocarmycin DMDrug-Linker Conjugates for ADCdrug-linkerDuocarmycin DMADCanticancerantibioticInhibitorinhibitorinhibit

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