2. Epigenetics Metabolic Enzyme/Protease
  3. Methionine Adenosyltransferase (MAT)
  4. MAT2A-IN-22

MAT2A-IN-22 (Compound 29-1) is a BBB-penatrable and orally active MAT2A inhibitor with an IC50 of 4 nM. MAT2A-IN-22 shows selectivity and inhibitory activity against MTAP-deficient cancer cell lines. MAT2A-IN-22 has anti-tumor effects.

For research use only. We do not sell to patients.

MAT2A-IN-22 Chemical Structure

MAT2A-IN-22 Chemical Structure

CAS No. : 2925330-18-1

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Description

MAT2A-IN-22 (Compound 29-1) is a BBB-penatrable and orally active MAT2A inhibitor with an IC50 of 4 nM. MAT2A-IN-22 shows selectivity and inhibitory activity against MTAP-deficient cancer cell lines. MAT2A-IN-22 has anti-tumor effects[1].

Molecular Weight

348.34

Formula

C18H11D3F3N3O
CAS No.
SMILES

O=C1[C@]2(C3=CC(C(F)(F)F)=CC=C3C(NC([2H])([2H])[2H])=N1)C4=CC=CN=C4CC2
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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MAT2A-IN-22 Related Classifications

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Keywords:

MAT2A-IN-222925330-18-1Methionine Adenosyltransferase (MAT)S-adenosylmethionine SynthetaseHCT-116 cellsColorectal cancer modelInhibitorinhibitorinhibit

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HY-170905S
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