1. Anti-infection
  2. Bacterial
  3. MBX-1066

MBX 1066 is a potent antibacterial agent. MBX 1066 shows inhibition for Mycobacterium tuberculosis. MBX 1066 shows antibacterial activity in mice.

For research use only. We do not sell to patients.

MBX-1066 Chemical Structure

MBX-1066 Chemical Structure

CAS No. : 868971-24-8

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Description

MBX 1066 is a potent antibacterial agent. MBX 1066 shows inhibition for Mycobacterium tuberculosis. MBX 1066 shows antibacterial activity in mice[1].

In Vitro

MBX 1066 shows cytotoxicity for HeLa cells with a CC50 value of 33 µg/mL[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

MBX 1066 (1, 10 mg/kg; i.v.; single dose, one hour post infection) shows antibacterial activity and increases the mice survival[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: ICR/Swiss Webster mice (Staphylococcus aureus strain NRS384) [1]
Dosage: 1, 10 mg/kg
Administration: I.v.; single dose, one hour post infection
Result: Increased the survival in a dose-dependent maner.
Molecular Weight

444.53

Formula

C28H24N6

CAS No.
SMILES

C1(C2=CC=C(C=C2)C3=CC4=C(C=C(C=C4)C5=NCCN5)N3)=CC6=C(C=C(C=C6)C7=NCCN7)N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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MBX-1066 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
MBX-1066
Cat. No.:
HY-129318
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