1. Anti-infection
  2. Bacterial
  3. MBX3135

MBX3135 is an efflux pump inhibitor which can enhance the effect of antibiotics through the AcrB target of bacteria. MBX3135 can be used for research of infection and antibiotics.

For research use only. We do not sell to patients.

MBX3135 Chemical Structure

MBX3135 Chemical Structure

CAS No. : 1636878-36-8

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Description

MBX3135 is an efflux pump inhibitor which can enhance the effect of antibiotics through the AcrB target of bacteria. MBX3135 can be used for research of infection and antibiotics[1].

In Vitro

MBX3135 (0.024-0.39 μM, 4 h) potentiates the bactericidal activity of a minimally bactericidal dose of ciprofloxacin (0.01 μg/mL) against E. coli[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

506.66

Formula

C28H34N4O3S

CAS No.
SMILES

C=CC(NC1=CC=C(C=C1)CCSC2=NC(N3CC(OC(C3)C)C)=C4COC(C)(CC4=C2C#N)C)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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MBX3135 Related Classifications

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
MBX3135
Cat. No.:
HY-157987
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