2. Academic Validation
  3. KR025, a new cytotoxic compound from Myxococcus fulvus

KR025, a new cytotoxic compound from Myxococcus fulvus

  • J Nat Prod. 1999 Mar;62(3):495-6. doi: 10.1021/np9804233.
J W Ahn 1,  S H Woo,  C O Lee,  K Y Cho,  B S Kim
Affiliations

Affiliation

  • 1 Korea Research Institute of Chemical Technology, P.O. Box 107, Taejon 305-600, Korea. jwahn@pado.krict.re.kr
PMID: 10096868 DOI: 10.1021/np9804233
Abstract

A new bithiazole, KR-025 (1), was isolated from Myxococcus fulvus. Its structure was elucidated by spectroscopic analysis. In addition to 1, the strain produced relatively large quantities of a second, closely related Antibiotic, myxothiazol. These compounds demonstrated potent cytotoxicity against human tumor cells.

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