2. Academic Validation
  3. Isolation of taxoids from cell suspension cultures of Taxus wallichiana

Isolation of taxoids from cell suspension cultures of Taxus wallichiana

  • Planta Med. 2000 Dec;66(8):773-5. doi: 10.1055/s-2000-9782.
S Agrawal,  S Banerjee,  S K Chattopadhyay,  M Kulshrestha,  K P Madhusudanan,  V K Mehta,  S Kumar
PMID: 11199143 DOI: 10.1055/s-2000-9782
Abstract

Cell suspension cultures of stem-derived callus of Taxus wallichiana in MS-F culture media were found to produce three C-14 oxygenated taxoids and one regular taxoid. The taxoids were identified as yunnanxane (1), 2 alpha, 5 alpha, 10 beta, 14 beta-tetraacetoxy-4(20),11-taxadiene (2), 2 alpha, 5 alpha, 10 beta-triacetoxy-14 beta-(2-methyl)-butyryloxy-4(20),11-taxadiene (3) and 1 beta-hydroxybaccatin I (4).

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