1. Academic Validation
  2. Naphthopyranone glycosides from Paepalanthus microphyllus

Naphthopyranone glycosides from Paepalanthus microphyllus

  • J Nat Prod. 2001 May;64(5):680-2. doi: 10.1021/np000518g.
S Piacente 1 L Campaner Dos Santos N Mahmood A Zampelli C Pizza W Vilegas
Affiliations

Affiliation

  • 1 Dipartimento di Scienze Farmaceutiche, Università degli Studi di Salerno, Via Ponte Don Melillo 84084, Fisciano, SA, Italy.
Abstract

Three new naphthopyranone glycosides, paepalantine-9-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranoside (1), paepalantine-9-O-alpha-L-arabinopyranosyl-(1-->6)-beta-D-glucopyranoside (2), and paepalantine-9-O-alpha-L-rhamnopyranosyl-(1-->6)-beta-D-glucopyranoside (3), along with the known paepalantine-9-O-beta-D-glucopyranoside (4) were isolated from aerial parts of Paepalanthus microphyllus. These compounds were characterized by spectrometric methods, including electrospray mass spectrometry and 1D and 2D NMR experiments. As a part of our program for screening natural compounds for anti-HIV activity, compounds 1-4 were tested in C8166 cells infected with HIV-1MN.

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