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  3. Catharanthus alkaloids XXXII: isolation of alkaloids from Catharanthus trichophyllus roots and structure elucidation of cathaphylline

Catharanthus alkaloids XXXII: isolation of alkaloids from Catharanthus trichophyllus roots and structure elucidation of cathaphylline

  • J Pharm Sci. 1976 Mar;65(3):366-9. doi: 10.1002/jps.2600650312.
G A Cordell,  N R Farnsworth
PMID: 1263083 DOI: 10.1002/jps.2600650312
Abstract

Further examination of the cytotoxic alkaloid fractions of Catharanthus trichophyllus roots afforded nine Alkaloids. Two of these Alkaloids, lochnericine and horhammericine, are responsible for part of the cytotoxic activity. The structure elucidation of cathaphylline, a new beta-anilino acrylate derivative, is described.

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