2. Academic Validation
  3. Prenylated xanthones from Garcinia xanthochymus

Prenylated xanthones from Garcinia xanthochymus

  • Chem Pharm Bull (Tokyo). 2003 Nov;51(11):1332-4. doi: 10.1248/cpb.51.1332.
Wisinee Chanmahasathien 1,  Yushan Li,  Masayuki Satake,  Yasukatsu Oshima,  Masami Ishibashi,  Nijsiri Ruangrungsi,  Yasushi Ohizumi
Affiliations

Affiliation

  • 1 Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba, Aramaki, Aoba-ku, Sendai 980-8578, Japan.
PMID: 14600386 DOI: 10.1248/cpb.51.1332
Abstract

A new prenylated xanthone, 1,3,5,6-tetrahydroxy-4,7,8-tri(3-methyl-2-butenyl)xanthone (1), was isolated from the wood of Garcinia xanthochymus together with a known xanthone, garciniaxanthone E (2). Their structures were determined by spectroscopic analysis. Compounds 1 (3 microM) and 2 (10 microM) elicited marked enhancement of nerve growth factor-mediated neurite outgrowth in PC12D cells.

Figures
Products