2. Academic Validation
  3. Doxorubicin prodrug on the basis of tert-butyl cephalosporanate sulfones

Doxorubicin prodrug on the basis of tert-butyl cephalosporanate sulfones

  • Bioorg Med Chem Lett. 2004 Feb 23;14(4):1007-10. doi: 10.1016/j.bmcl.2003.11.071.
Grigory Veinberg 1,  Irina Shestakova,  Maxim Vorona,  Iveta Kanepe,  Ilona Domrachova,  Edmunds Lukevics
Affiliations

Affiliation

  • 1 Latvian Institute of Organic Synthesis, 21 Aizkraukles Street, Riga, LV 1006, Latvia. veinberg@osi.lv
PMID: 15013011 DOI: 10.1016/j.bmcl.2003.11.071
Abstract

Doxorubicin-cephalosporin prodrug adapted to the development of elastases for the liberation of parent drug was synthesized on the basis of cephalosporanate sulfone esters.

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