2. Academic Validation
  3. Eye colour: portals into pigmentation genes and ancestry

Eye colour: portals into pigmentation genes and ancestry

  • Trends Genet. 2004 Aug;20(8):327-32. doi: 10.1016/j.tig.2004.06.010.
Richard A Sturm 1,  Tony N Frudakis
Affiliations

Affiliation

  • 1 Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland 4072, Australia. R.Sturm@imb.uq.edu.au
PMID: 15262401 DOI: 10.1016/j.tig.2004.06.010
Abstract

Several recent papers have tried to address the genetic determination of eye colour via microsatellite linkage, testing of pigmentation candidate gene polymorphisms and the genome wide analysis of SNP markers that are informative for ancestry. These studies show that the OCA2 gene on chromosome 15 is the major determinant of brown and/or blue eye colour but also indicate that Other loci will be involved in the broad range of hues seen in this trait in Europeans.

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