2. Academic Validation
  3. Lupane triterpenoids from Maytenus species

Lupane triterpenoids from Maytenus species

  • J Nat Prod. 2005 Jul;68(7):1018-21. doi: 10.1021/np058016w.
Marvin J Núñez 1,  Carolina P Reyes,  Ignacio A Jiménez,  Laila Moujir,  Isabel L Bazzocchi
Affiliations

Affiliation

  • 1 Instituto Universitario de Bio-Orgánica Antonio González, Universidad de La Laguna, and Instituto Canario de Investigación del Cáncer, Avenida Astrofísico Francisco Sánchez 2, 38206 La Laguna, Tenerife, Spain.
PMID: 16038541 DOI: 10.1021/np058016w
Abstract

Five new lupane Triterpenes (1-5), in addition to 24 known ones, were isolated from Maytenus cuzcoina and M. chiapensis. Their structures were elucidated on the basis of spectroscopic analysis, including homonuclear and heteronuclear correlation NMR (COSY, ROESY, HSQC, and HMBC) experiments. The compounds were assayed for antimicrobial and cytotoxic activities, with 3-epi-betulinic acid and 28,30-dihydroxy-3-oxolup-20(29)-ene showing moderate cytotoxicity.

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