2. Academic Validation
  3. Wisteria floribunda lectin is associated with specific cell types in the ventral cochlear nucleus of the gerbil, Meriones unguiculatus

Wisteria floribunda lectin is associated with specific cell types in the ventral cochlear nucleus of the gerbil, Meriones unguiculatus

  • Hear Res. 2006 Jun-Jul:216-217:64-72. doi: 10.1016/j.heares.2006.01.008.
Nell B Cant 1,  Christina G Benson
Affiliations

Affiliation

  • 1 Department of Neurobiology, Duke University Medical Center, P.O. Box 3209, 213 Bryan Research Building, Durham, NC 27710, USA. nellcant@neuro.duke.edu
PMID: 16497454 DOI: 10.1016/j.heares.2006.01.008
Abstract

The cochlear nucleus is made up of a number of diverse cell types with different anatomical and physiological properties. A plant lectin, Wisteria floribunda agglutinin, that recognizes specific carbohydrate residues in the extracellular matrix binds to some cell types in the ventral cochlear nucleus but not to cells in the dorsal cochlear nucleus. In the ventral cochlear nucleus, the most intensely labeled cells are octopus cells, a subset of multipolar cells and cochlear root neurons. The multipolar cells that are labeled may correspond to the population that projects to the inferior colliculus.

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