2. Academic Validation
  3. Antibacterial properties of the bicyclic pyrazolidinones

Antibacterial properties of the bicyclic pyrazolidinones

  • J Antibiot (Tokyo). 1990 Jan;43(1):92-9. doi: 10.7164/antibiotics.43.92.
N E Allen 1,  J N Hobbs Jr,  D A Preston,  J R Turner,  C Y Wu
Affiliations

Affiliation

  • 1 Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana 46285.
PMID: 1689710 DOI: 10.7164/antibiotics.43.92
Abstract

LY173013 and LY186826 are bicyclic pyrazolidinones containing a novel aza-gamma-lactam ring structure. The Antibacterial properties of these compounds appear to be related to those of Beta-lactam Antibiotics in that both classes of compounds share certain common binding molecules such as beta-lactamases and penicillin-binding proteins.

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