2. Academic Validation
  3. Hereditary pyropoikilocytosis: a rare but potentially severe form of congenital hemolytic anemia

Hereditary pyropoikilocytosis: a rare but potentially severe form of congenital hemolytic anemia

  • J Pediatr Hematol Oncol. 2007 Feb;29(2):128-9. doi: 10.1097/MPH.0b013e3180320b6f.
Maria C Ramos 1,  Kristian T Schafernak,  LoAnn C Peterson
Affiliations

Affiliation

  • 1 Department of Pathology, Division of Hematopathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
PMID: 17279012 DOI: 10.1097/MPH.0b013e3180320b6f
Abstract

Hereditary pyropoikilocytosis is an inherited red cell membrane disorder with characteristic morphology: striking anisopoikilocytosis with red cell fragmentation and microspherocytes. Clinical and laboratory physicians must be aware of the potential impact of this disorder on accuracy of complete blood count results reported by automated hematology instruments. Recognition of the morphologic and laboratory findings are important for recognizing this potentially severe anemia.

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