2. Academic Validation
  3. Phenalenone-type compounds from Musa acuminata var. "Yangambi km 5" (AAA) and their activity against Mycosphaerella fijiensis

Phenalenone-type compounds from Musa acuminata var. "Yangambi km 5" (AAA) and their activity against Mycosphaerella fijiensis

  • J Nat Prod. 2007 May;70(5):887-90. doi: 10.1021/np070091e.
Felipe Otálvaro 1,  Juliana Nanclares,  Luz Estella Vásquez,  Winston Quiñones,  Fernando Echeverri,  Rafael Arango,  Bernd Schneider
Affiliations

Affiliation

  • 1 Departamento de Ingeniería, Universidad Nacional de Colombia sede Palmira, Carrera 32 Chapinero vía Candelaria, A.A 237, Palmira-Valle del Cauca, Colombia. lfotalvarot@palmira.unal.edu.co
PMID: 17428093 DOI: 10.1021/np070091e
Abstract

Two perinaphthenone-type compounds (1 and 2) were isolated together with four known phenylphenalenones (3-6) from the rhizomes of Musa acuminata var. "Yangambi km 5". The structures of the new phenalenones were assigned as 2-hydroxy-1H-phenalen-1-one (1) and 2-methoxy-1H-phenalen-1-one (2) on the basis of their spectroscopic data and were confirmed by synthesis. Compounds 1 and 2 displayed significantly enhanced activity against Mycosphaerella fijiensis in comparison with other phenylphenalenones.

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