2. Academic Validation
  3. Triterpenoids from Schisandra rubriflora

Triterpenoids from Schisandra rubriflora

  • J Nat Prod. 2007 Jun;70(6):1056-9. doi: 10.1021/np0700927.
Wei-Lie Xiao 1,  Xiao-Li Li,  Rui-Rui Wang,  Liu-Meng Yang,  Li-Mei Li,  Sheng-Xiong Huang,  Jian-Xin Pu,  Yong-Tang Zheng,  Rong-Tao Li,  Han-Dong Sun
Affiliations

Affiliation

  • 1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, Yunnan, People's Republic of China.
PMID: 17489633 DOI: 10.1021/np0700927
Abstract

Investigation of an organic extract of Schisandra rubriflora led to the isolation of three new highly oxygenated nortriterpenoids, named rubriflorins A-C (1-3), together with six related known compounds (4-9). Their structures were elucidated by spectroscopic evidence. Compounds 1-3 feature the opening of ring A compared with related known nortriterpenoids isolated from the genus Schisandra and showed anti-HIV-1 activities with EC50 values of 10.0, 16.2, and 81.3 microg/mL, respectively.

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