2. Academic Validation
  3. Five novel prenylated xanthones from Resina Garciniae

Five novel prenylated xanthones from Resina Garciniae

  • J Asian Nat Prod Res. 2007 Sep-Dec;9(6-8):735-41. doi: 10.1080/10286020701189146.
Feng Feng 1,  Wen-Yuan Liu,  You-Sheng Chen,  Qing-Long Guo,  Qi-Dong You
Affiliations

Affiliation

  • 1 Department of Phytochemistry, China Pharmaceutical University, Nanjing, China.
PMID: 17994391 DOI: 10.1080/10286020701189146
Abstract

Fourteen prenylated xanthone derivatives were isolated from gamboge, the dry latex of Garcinia hanburyi, and their structures were elucidated by a detailed spectroscopic analysis. Five of them, isogambogenic acid (1), desoxymorellinin (2), 10-methoxygambogenic acid (3), 10-methoxygambogic acid (4) and 10-ethoxy gambogic acid (5), are new compounds. All of them showed potent cytotoxicity against HL-60, SMMC-7721 and BGC-83 cells.

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