2. Academic Validation
  3. Polyprenylated xanthones from Garcinia lancilimba showing apoptotic effects against HeLa-C3 cells

Polyprenylated xanthones from Garcinia lancilimba showing apoptotic effects against HeLa-C3 cells

  • Chem Biodivers. 2008 Dec;5(12):2710-7. doi: 10.1002/cbdv.200890225.
Quan-Bing Han 1,  Hong-Lei Tian,  Nian-Yun Yang,  Chun-Feng Qiao,  Jing-Zheng Song,  Donald C Chang,  Kathy Q Luo,  Hong-Xi Xu
Affiliations

Affiliation

  • 1 Chinese Medicine Laboratory, Hong Kong Jockey Club Institute of Chinese Medicine, Shatin, N. T., Hong Kong, P. R. China.
PMID: 19089829 DOI: 10.1002/cbdv.200890225
Abstract

Three new prenylated Xanthones, 1-3, along with ten known compounds, were isolated from the stem bark of Garcinia lancilimba. Their structures were elucidated by extensive spectroscopic analysis, including 1D- and 2D-NMR spectra, as well as HR-MS experiments. Some of these compounds showed apoptotic effects or growth-inhibition effects against HeLa cells expressing a Caspase sensor protein.

Figures
Products
  • Cat. No.
    Product Name
    Description
    Target
    Research Area
  • HY-N3347
    98.99%, Xanthone