2. Academic Validation
  3. Chloramultiols A-F, lindenane-type sesquiterpenoid dimers from Chloranthus multistachys

Chloramultiols A-F, lindenane-type sesquiterpenoid dimers from Chloranthus multistachys

  • J Nat Prod. 2010 May 28;73(5):972-5. doi: 10.1021/np900764n.
Xin-Hui Ran 1,  Fei Teng,  Chang-Xiang Chen,  Gang Wei,  Xiao-Jiang Hao,  Hai-Yang Liu
Affiliations

Affiliation

  • 1 State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, People's Republic of China.
PMID: 20392109 DOI: 10.1021/np900764n
Abstract

Six new highly complex lindenane-type sesquiterpenoid dimers, chloramultiols A-F (1-6), along with six known analogues, were isolated from the whole plant of Chloranthus multistachys. The structures of 1-6 were elucidated on the basis of mass spectrometry (MS) and 1D and 2D NMR spectroscopic analysis. Among them, compounds 1 and 6 contain a unique 18-membered macrocyclic triester ring. All compounds isolated were evaluated for the inhibition of the growth of five tumor cell lines.

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