2. Academic Validation
  3. Suppressive effect of Yamato-mana (Brassica rapa L. Oleifera Group) constituent 3-butenyl glucosinolate (gluconapin) on postprandial hypertriglyceridemia in mice

Suppressive effect of Yamato-mana (Brassica rapa L. Oleifera Group) constituent 3-butenyl glucosinolate (gluconapin) on postprandial hypertriglyceridemia in mice

  • Biosci Biotechnol Biochem. 2010;74(6):1286-9. doi: 10.1271/bbb.100018.
Kazuto Washida 1,  Mitsuyoshi Miyata,  Tomoyuki Koyama,  Kazunaga Yazawa,  Kyosuke Nomoto
Affiliations

Affiliation

  • 1 Nara Prefectural Small and Medium-sized Enterprises Support Corporation, Nara Prefectural Agricultural Experiment Station, Kashihara, Nara, Japan. kwashida@festa.ocn.ac.jp
PMID: 20530888 DOI: 10.1271/bbb.100018
Abstract

We examined the bioactivity of Yamato-mana (Brassica rapa L. Oleifera Group) constituent Glucosinolates and found that 3-butenyl glucosinolate (gluconapin) decreased the plasma triglyceride gain induced by corn oil administration to mice. However, phenethyl glucosinolate (gluconasturtiin) had little effect. 2-Propenyl glucosinolate (sinigrin) also reduced the plasma triglyceride level, which suggests that alkenyl Glucosinolates might be promising agents to prevent postprandial hypertriglyceridemia.

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