2. Academic Validation
  3. New monoterpenes, diterpenes, and lignans from Abies recurvata

New monoterpenes, diterpenes, and lignans from Abies recurvata

  • Planta Med. 2012 Sep;78(14):1574-8. doi: 10.1055/s-0032-1315111.
Yong-Li Li 1,  Ji-Gang Zhang,  Ping Yu,  Bei-Lei Ke,  Ji Ye,  Xian-Wen Yang,  Hui-Zi Jin,  Wei-Dong Zhang
Affiliations

Affiliation

  • 1 School of Pharmacy, Shanghai Jiao Tong University, Shanghai, China.
PMID: 22814888 DOI: 10.1055/s-0032-1315111
Abstract

From the aerial part of Abies recurvata, 62 miscellaneous chemical constituents were isolated including 6 new and 56 known ones. The new compounds comprised three monoterpenes, two diterpenes, and one lignan. Their chemical structures were characterized on the basis of various spectroscopic techniques. Dihydrodehydrodiconiferyl alcohol (35) showed the strongest inhibitory effects against lipopolysaccharide-induced nitric oxide production in RAW 264.7 cells with an IC₅₀ value of 66.4 µM.

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