1. Academic Validation
  2. Nine new steroidal glycosides from the roots of Cynanchum stauntonii

Nine new steroidal glycosides from the roots of Cynanchum stauntonii

  • Steroids. 2013 Jan;78(1):79-90. doi: 10.1016/j.steroids.2012.10.007.
Jin-Qian Yu 1 An-Jun Deng Hai-Lin Qin
Affiliations

Affiliation

  • 1 State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, PR China. fish@imm.ac.cn
Abstract

Nine new steroidal glycosides, named as stauntosides C-K (2, 5, 7-10, 13, 14, and 16), along with seven known compounds (1, 3, 4, 6, 11, 12, and 15) were isolated from the 95% ethanol extract of the roots of Cynanchum stauntonii. The structures of these new compounds were elucidated on the basis of extensive spectroscopic analyses, mainly 1D and 2D NMR, and HRESI-MS, and qualitative chemical methods. Their significance in terms of the chemotaxonomy of C. stauntonii is discussed.

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